Thursday, August 27, 2020

Taxation Master Case Study Example | Topics and Well Written Essays - 5000 words

Tax collection Master - Case Study Example Then again, in figuring charge obligation of enterprises, we utilize the Financial Year. Monetary Year runs from 1 April in one year and closures on 31 March of the next year. For tax collection purposes, available benefits by an organization for Financial Year 2008 are those acquired from 1 April 2008 to 31 March 2009. Personal expense is an assessment on pay. Not all pay is available and you're just burdened on 'available salary' over a specific level. And still, at the end of the day, there are different reliefs and stipends that can decrease your Income Tax Bill - and sometimes mean you have no duty to pay (Income Tax - the Basics). Non - available salary are sure kinds of pay that you never make good on charge. These incorporate certain advantages, annual duty absolved records, Working Tax Credit (WTC) and premium security wins. These salary sources are overlooked by and large when turning out to be and the amount Income Tax you may need to pay. (Annual Tax - the nuts and bolts) Hitched Couple's Allowance (incorporates common association)- in the event that you are hitched or in a common organization, you or your accomplice may get Married Couple's Allowance (MCA) on the off chance that you are living respectively and you and your companion or common accomplice were conceived before 6 April 1935. The sum you will get relies upon the age of the most seasoned mate/common accomplice and the degree of inquirer's pay. Your expense bill will be decreased by (10%) of the measure of the MCA you can guarantee. (Prologue to burden recompenses and reliefs) Different stipends, reliefs and costs You can get charge alleviation for various costs, depending whether you are a worker or executive or independently employed. On the off chance that you are a worker or a chief, you can get charge help for operational expense you have paid for and on the off chance that: they were for the expense of venturing out you needed to do in carrying out your responsibility, and different costs you

Saturday, August 22, 2020

Indian Schools

Local American Assimilation into Western Culture Throughout the 1800s and the mid 1900s, the American government endeavored to absorb Native American youngsters into the Western culture, with all the best aims (Marr Intro). Through essential and optional sources, we figure out how this was done and the errors they made in doing it. Essential sources, which are archives or different wellsprings of data made at or close to the time an occasion happened, are a fundamental part in comprehension history.There are numerous essential sources in the paper â€Å"Assimilation Through Education: Indian Boarding Schools in the Pacific Northwest† via Carolyn J. Marr including: photos, transcripts, diary sections, and government records. The utilization of photos has numerous points of interest and impediments. Photos are genuinely exact in depicting an occasion. It gives the peruser a lot of proof and a vibe for how the subjects were feeling during the occasion by indicating feelings or ou tward appearances that couldn't be communicated through composed word.On the other hand, they could be extremely one-sided as to show the harshest or most ideal conditions. A photograph is only a concise preview of a second in time, and doesn't show an entire occasion that a journal or diary may tell. Likewise, a picture taker might be one-sided towards their very own perspectives, age, religion, social, monetary, or political foundation; all of which may impact what the individual in question will or won’t photo. Finally, it is additionally not in every case clear where a photograph was taken, why, and by whom. Auxiliary sources demonstrate to serve a significant job in deciphering history.They incorporate records, books, or articles, through translations by students of history. A few books and reports utilized in Marr’s exposition are: Carey C. Collins’ â€Å"Oregon's Carlisle: Teaching ‘America? at Chemawa Indian School†, Carey C. Collins’ â€Å"Through the Lens of Assimilation: Edwin L. Chalcraft and Chemawa Indian School†, and Michael C. Coleman’s American Indian Children at School. These sources disclose the government’s endeavors to absorb (the demonstration of turning out to be a piece of something) Indians, especially kids, into the blend of American culture. This occurred from the 1800s through the 1920s (Marr Intro).I trust it was vital for the administration to endeavor to bring Indians into the American culture, however I don't accept they did it effectively. Greatening instruction, expanding strict and social perspectives, and making solid bonds between different understudies were a portion of the benefits of this development. Children likewise got running water, power, tolerable food and clean garments. Sadly, the insidiousness done incredibly exceeded the great. They took kids from their folks and it was done so quickly, it didn’t permit Indians to attempt to move themselves a nd their youngsters into western culture.Taking endlessly their through and through freedom, tearing them away from their folks, offering terrible eating routines, packing schools, poor clinical consideration, and over the top constrained work by the understudies end up being a portion of the missteps made by the government’s drive into the â€Å"American† culture (Marr Part V). The organizations focused on business related preparing to profit the establishment instead of the youngsters, like bondage. It permitted the organizations to spend less by compelling free work onto the youngsters in fields, for example, cultivating, cooking, cleaning, blacksmithing, carpentry, and so forth. Marr Part IV). This diminished the recruited work required to run the huge organizations. This sort program permitted the understudies to learn exchange one needs to endure, however for the individuals who had aspirations to become something else, the foundation would not permit it (Marr Pa rt IV). All things being equal, Native American culture was assaulted by our legislature trying to better their lives. Sadly, they gave an environment of servitude and abuse in the most exacting translation of the words. Works Cited Collins, Carey C. â€Å"Oregon's Carlisle: Teaching ‘America? t Chemawa Indian School,† Columbia: The Magazine of Northwest History, Tacoma: Washington State Historical Society, Summer 1998. Collins, Carey C. â€Å"Through the Lens of Assimilation: Edwin L. Chalcraft and Chemawa Indian School,† Oregon Historical Quarterly v. 98, no. 14 (Winter 1997-98): 390-425. Coleman, Michael C. Native American Children at School, 1950-1930. Jackson: University Press of Mississippi, 1993. Marr, Carolyn J. â€Å"Assimilation Through Education: Indian Boarding Schools in the Pacific Northwest. † UW Libraries Digital Collections. Web. 09 Sept. 2010. <http://content. lib. washington. edu/aipnw/marr. html>.

Friday, August 21, 2020

College Board Essay Samples Can Help You

College Board Essay Samples Can Help YouCollege Board essay samples can help you get started when it comes to preparing for the exam that you need to be successful on. In fact, with just a few keystrokes, you could have a very good chance of passing with high marks. Just keep in mind some things before you buy your own.There are a lot of opportunities to find sample essays that can be printed out and studied or used as a guide for how to write an essay. You could go down to your local college bookstore, where there are many different kinds of literature. You can also search for the bookstores online and find as many essay samples as you can afford.Before you even begin looking for essays, you need to prepare a few things about your personal background and academic background. The essay samples that you are looking for should address your strengths and weaknesses. They should also discuss your strengths and weaknesses as a person. It would be even better if the college essay samples c ould be tailored to fit your particular needs.Some of the essays that you find with essay samples are also written by someone else. The people who write the sample essays are usually much more knowledgeable on how to write an essay than you are, and that is why they put the work into it. That means that you can also take the information that these people can bring to the writing table and adapt them for your own needs.When you are browsing through essay samples at the bookstore or at the online websites of the College Board, try to find one that is specifically made for students, and even one that is for teachers as well. There are a lot of college essay examples that focus on specific areas of study. These include but are not limited to, American history, English, economics, foreign languages, math, physics, and other subjects. You can also look for college essay samples that focus on self-help tips, crafts, sports, and hobbies as well.As you study, you will start to realize that n ot all people in the academic community are the same. There are a lot of differences in personalities, styles, and beliefs. If you want to have a good chance of writing an essay well, you have to learn as much as you can about the people that you are going to be dealing with.When you are ready to write your essay, you must be willing to put in the effort. This might sound overwhelming to you, but it is essential that you put in the time and effort that you need to make sure that you are prepared. Many students don't put as much effort into their essay, because they believe that their professors are more than willing to help them through. That is not the case at all.The best way to approach this essay is to find a place online that has a large selection of essay samples. From there, you can decide which essay samples will work best for you and look for people that have a similar background and perspective as you. Using these people as a resource will help you and your professor reall y help you with your assignment.

Tuesday, May 26, 2020

Romanticism in Mark Twains Tom Sawyer Essay - 1935 Words

Mark twain was an Interesting man who wrote about many books some about boyhood tales about adventure like Huckleberry Finn and Tom Sawyer. The book is full of Romanticism as the young boy Tom sawyer does his mischievous deeds like playing hooky from school and avoiding punishment by tricking his friends to white wash the fence in the beginning of the story. ‘’I have never let my schooling interfere with my education`` by mark Twain show the humor and depth behind his words. It illustrates how individuals learn the basics in school and do their real learning outside through experiences and trying new things. In the Mark Twain he became an apprentice ‘cub’ river pilot under Horace Bixby, earning his license in 1858. In that his†¦show more content†¦This lead to more rural people who did not usually take to book more inclined to make a more formidable library for their homes. The printing press help make books more available to the wider market during that time combined to make great literacy levels because there were more books. The romantic era of writing started in the 1830-1865 in America stemming from European Romanticism caused by the Civil war. Mark Twain simply wanted to improve on his book huckleberry Finn. His books were mainly realism but in this Novel it classifies as Romanticism. The major Authors tat influenced the genre were Edmund Burque, William Blake, Lord Byron, Francisco de Goya, Theodore Gericault. Romantic pieces consisted of heavy emotion and had its plot loosely reality based. Mark Twain had an interesting life. Mark twain was from Florida Missouri where he was surround by racism and cruelty like racism. He was born to a poor family and when his Father died in 1847 when young Samuel Langhorne Clemens left school in 5th grade he became a newspaper apprentice to provide income to the household. He also started writing his first stories A Gallant Fireman in 1851 and The Dandy Frightening the Squatter in 1852 along with little exerts here and there in the newspaper. Samuel didn’t really like his job at the newspaper all the well and became a steamboat pilot in 1858. Samuel became a very skilled Steam boat pilotShow MoreRelatedResearch Paper Mark Twain1306 Words   |  6 PagesIsabella Thomaz Donna Hunter - Period 2 Research Paper - Mark Twain October 26, 2012 MARK TWAIN: A REMARKABLE MAN WHO PAINTED THE WORLD â€Å"Classic - a book which people praise and dont read.† When Samuel L. Clemens (more often referred to as Mark Twain) said this, he meant it in a humorous sense, but he also wanted people to understand it’s meaning. People call books like Huck Finn and Gatsby classics, yet the idea that these books are actually read by everyone isn’t so. Twain isn’t justRead MoreRealism In Huck Finn Essay876 Words   |  4 Pagesthis literary style are the insistence upon and defence of the â€Å"commonplace†, characters being more important than plot, attacks upon romanticism and romantic writers, an emphasis on morality, which is often self-realized and upon an examination of realism, and the concept of realism as a realization of democracy. The Adventures of Huckleberry Finn , written by Mark Twain, is a perfect archetype of a novel written in the style of realism, as it satisfies all of the aforementioned principles thatRead MoreMark Twain s The Racism Of His Time1358 Words   |  6 Pages In response to the racism of his time, Mark Twain uses The Adventures of Huckleberry Finn to contend that racism is an artificial, manufactured product of civilization that supplants the ingrained, human resistance to injustices like racism. To substantiate this point, Twain interweaves the reoccurring motifs of the instinctive feeling of sickness, the effects of a civilized upbringing, and the presence of romanticism into the story. Throughout the book, the titular protagonist, Huckleberry FinnRead MoreMark Twain’s The Adventures of Huckleberry Finn Essay1103 Words   |  5 Pages Published in 1885, Mark Twain’s American classic, The Adventures of Huckleberry Finn, captured the both the hearts and hatred of its audience. While some view it as a masterpiece that successfully blended the American condition in a captivating and interesting manner, others observe it to be nothing more than racist trash. The latter is a shallow misunderstanding of the novel’s purpose and potential enlightening impact on its readers. From a more appreciative and open-minded perspective, one wouldRead MoreHuckleberry Finn: Realism vs. Romanticism1010 Words   |  5 PagesHuckleberry Finn: Realism vs. Romanticism The Adventures of Huckleberry Finn, written by Mark Twain, mainly takes place on the Mississippi River, as Huck and Jim pursue their freedom. They persevere through many obstacles and learn life lessons along the way. Twain uses these characters to depict the significance of friendship over societys moral structure. He demonstrates characteristics of both Romanticism and Realism in his novel to express his ideas of that time period. Romanticism is based on the importanceRead MoreSatire : Satire And Satire1498 Words   |  6 Pagesman s name was Mark Twain and he used his intimate knowledge of life in the South to write several satirical works commenting on the more disagreeable practices of Southern society. His most famous satirical work, The Adventures of Huckleberry Finn is rife with satirical commentary on topics such as racism, religion, and romanticism. In this novel, Twain uses his satirical skills to criticize what he views as negative aspects of Southern society, aspects su ch as racism, romanticism, and certain aspectsRead MoreTom Sawyer : Little Rascal And Proper Southern Gentleman1696 Words   |  7 PagesTom Sawyer: Little Rascal and Proper Southern Gentleman In The Adventures of Huckleberry Finn, Tom Sawyer appears in St Petersburg and at the Phelps’ farm as Huck Finn’s companion. Though Tom serves as Huck’s partner-in-crime of sorts, the two boys contrast in crucial perceptual and behavioral aspects: where Tom possesses a love for romanticism and a strict policy of adherence to societal conventions and codes, Huck possesses a skeptical sort of personality in which he tends to perceive society’sRead MoreReview Of The Of The Imagination Essay1852 Words   |  8 Pages CHAPTER – II REALISM IN MARK TWAINS NOVELS According to Irving Babbitt, the imagination plays an all-important role in both literature and life. For Babbitt, society and politics are shaped by the imagination, because it is within the context of the imagination that one’s reason and will inevitably function. He explains that man is cut off from immediate contact with anything abiding and therefore worthy to be called real, and condemned to live in an element of fiction or illusion, but he mayRead MoreEssay about Mark Twain1654 Words   |  7 PagesMark Twain Mark Twain is believed to be the father of all American literature. Twain was known for writing about issues of his time such as slavery, due to his style of honesty and truth he was known as one of the very first modernist writers. Mark Twain had many inspirations that motivated him to write his novels. The inspirations varied from events that he witnessed and experienced, people he met in his lifetime, other stories he read or heard about, and his environment. The writer knownRead More Escaping Reality in Mark Twains The Adventures of Huckleberry Finn1306 Words   |  6 PagesRunning From Reality in Huckleberry Finn        Ã‚  Ã‚   In Mark Twains The Adventures of Huckleberry Finn, a main target of satire is the romantic view of life. Though the characters and symbols, it is evident that the idyllic views are being disparaged. Some of the people in this book are simply deluded, while others cause major tribulations during their lives. Literary romanticism can be pleasant, but it is not real and can confuse those not sage enough to distinguish the difference between a writers

Friday, May 15, 2020

The Elements of an Effective Relationships and Daily Strains

Relationships can work with the right ingredients! This paper will define the elements of an effective relationship and the strains pulling on those relations daily. Acknowledging those components could improve the quality and success of the relationship. Historically, relationships go back to the beginning of time. Relationships are governed by commandments and traditions.Keep in mind, background is a huge influence on people actions in a relationship. Relationship is defined as a correlation by blood or matrimony. The evolution of relationships keeps evolving with times. For example, the relationship between man and man or woman and woman was unaccepted. In today society, a same gender relationship is acceptable. Reflecting back, a†¦show more content†¦Commitment in a relationship will institute stability and an advantage past development. The processes of commitment are defining the meaning; understanding the role; and, building on maturity of the relationship (pp.188-189). Lauer Lauer (2012) suggested: â€Å"In essence, then, commitment means a promise of dedication to a relationship in which there is an emotional attachment to another person who has made the same promise. It is important to note that the commitment is to the person and not simply to the institution of marriage. One difference between long-term satisfying marriages and those that are long-term but unsatisfying is that people in the former are committed to the spouse while people in the latter are committed more to the institution† (p.189). In summary, commitment is the epitome of the bond between both partners. The relationship core is factor on a mutual commitment. People that are happy focus on their mate and the unhappy people focal point is on tradition. Marriage and Family Next ingredients in most relationships are marriage and family. Funny, marriage and family is like salt and pepper. They are all based upon the individual choice in life.People get married for several reason for instance; love, lifestyle, ideals, and children (pp.176-177). Marriage is the amalgamation of a man and a woman confessing their love and vows to God.As previously stated, the same sex genders are allowed to getShow MoreRelatedExecuting An Effective Iep Meeting Requires Multiple Elements955 Words   |  4 PagesExecuting an effective IEP meeting requires multiple elements, as various key stakeholders are involved within the process. As a special education program specialist I have daily opportunities to participate in an Individualized Education Plans (IEPs). Typically, my involvement is stemmed from high profile cases in which litigation is anticipated or has transpired within the past. My role is to represent the district and aid in the development of an appropriate offer of a free and appropriateRead MoreGambling Outline Essay912 Words   |  4 Pagesa stake, and there is a pay-off. â€Å"Here is the definition of gamble – to play at any game of chance for stakes, to bet on an uncertain outcome† (Brown). â€Å"The following three elements must be present for something to be defined as gambling: a pay-off, the element of chance, and the stake risked by the bettor† (Brown). B. Many events could be considered gambling, but the most popular form of gambling is lotteries. â€Å"Some types of gambling are gamingRead MoreActive And Working : Managing Acute Low Back Pain Essay1741 Words   |  7 Pagesactivities – or it may even occur for no known reason. It often starts with an activity of daily living that might not have cause any pain before. Acute back pain can also be caused by an accident such as slipping or falling (National Health Committee, 2000). Many studies have been done and there are still debates over the risk factors for back pain. There is some evidence that heavy lifting that strains the back, sudden and forceful movement, bending while bearing weight, and lots of lifting areRead MoreHuman Resource Management Final Exam1431 Words   |  6 Pagesï » ¿Qi Jiang Foundation MPHR 696 Final Exam Jan 23rd, 2014 Question 1: Collective Bargaining A labor relation is a key issue for organizations because the nature of the relationship between employees and employers can have a significant impact on morale, motivation and productivity. The act allows unions to be formed and exist as employee organizations that have the legal rights to bargain with management over various terms and conditions of employment. When a union is elected toRead MoreThe Elements Of Management As A Tool For Solving Problems1441 Words   |  6 PagesElements of management should be guided by the human physical dynamism of organizational units, which seeks to attain the objective and the satisfaction of an organization (Robbins Judge, 2015). Management is guiding human and physical resources into dynamic organizational units which attain their objectives to the satisfaction of those served and with a high degree of morale and sense of attainment on the part of those rendering service. —American Management Association The aim of this reportRead MoreTechnology and Social Change in Healthcare1606 Words   |  7 Pagesand how it has changed the way people and corporations function in society. Over the past several years the technological growth and availability of laptops, computers, cellular phones and the Internet have changed society and how we function on a daily basis. Parents can use Global Positioning System also known as GPS on their devices to keep track of their children as well as â€Å"on the go† conference calls via cell phones for work. From a personal perspective the computer and Internet have providedRead MoreThe Importance of Ecosystem Management and Protection.1510 Words   |  7 PagesRecent growth in scientific knowledge has helped humanity comprehend the complex relationships in ecosystems and the devastating effects of human interference. As a result we have become increasingly aware of the need to protect and manage the ecosystems that we do have remaining for their utility, genetic, intrinsic and heritage values and also for the need to allow natural change and thus evolution to take place. Natural ecosystems have provided much that has be en of benefit to humanity and withRead MoreProblems and Challenges Facing Probation1624 Words   |  7 Pagespermit his reincarceration in the event of misbehavior? (p.437 Allen et al). Parole seems like a reasonable and effective way to get prisoners back on the streets, rehabilitated and helping out the community, but parole still faces many challenges and problems. More and more inmates are being let out on parole, but at the same time, parole boards are losing funding. This puts a strain on parole officers and leaves many parolees unsupervised. It is problems like this that lead to parolees ending upRead MoreEssay on Transition to a Professional Nursing1450 Words   |  6 Pageswith a commitment to the role (Blais amp; Hayes, 2011). Changes in the healthcare system affect society’s expectation of nursing care. Due to these high expectations, nurses are returning to school in order to satisfy these prospects and are more effective in their roles. Prospective nursing stud ents and registered nurses that are returning to school are undergoing many of the challenges described in these two models of transition. I recently change my work place and after studying the different modelsRead MoreMedia And Its Effect On Society2385 Words   |  10 Pagessciences unveil the conceivable impact of mass communications and correspondences on society. Researchers have created various methodologies and hypotheses to make sense of this. Different researchers challenge whether examination can ever unwind the relationship of media and impacts. This paper illustrates these theories on the media s impact on people and society. Mass Society Theory The term typically conveys pessimistic intentions, alluding to the masses or the common individuals who are portrayed

Wednesday, May 6, 2020

Gender Roles Are Defined By The Roles Or Behaviours Learned

Gender roles are defined by the roles or behaviours learned by a person as appropriate to their gender, determined by the prevailing cultural norms. Gender roles are based on norms or standards, created by society. In American culture masculine roles have traditionally been linked with strength, aggression, and dominance, while feminine roles have traditionally been associated with passivity, nurturing, and being submissive. Gender socialization starts and occurs throughout the four major agents of socialization of peer groups, family, mass media, and education. Throughout this repeated socialization over time leads men and women into a false sense that they are acting naturally rather than following a socially constructed role created by†¦show more content†¦That throughout the ages one main discussions about gender roles in the United States has been the historical evolution from a single-income family, or a family unit in which one spouse typically the father is responsi ble for the family income to to a dual-income family, or a family unit in which both spouses generate income.That before the rise of feminism in the 1960s and 1970s and the influx of women into the workforce in the 1980s, women were largely responsible for dealing with home matters while men worked and earned income outside the home. Which was a radical change since women would be primarily focused on housekeeping, childcare, and children s education while the men’s participation in domestic activity would be only partially desired and socially acceptable.With the popularization of social constructionist theories of gender roles, it is paramount that one recognize that all assertions about gender roles are culturally and historically contingent.Which means that what might be true of gender roles in the United States for one cultural group likely is not true for another cultural group. The roles played by the members of each gender in American society reflects a burgeoning problem about the lack of equality between the sexes. Women in America usually still fulfill the role of â€Å"homemaker.† Woman are still regarded as the caretaker ofShow MoreRelatedSocial Constructionism And Biological Determinism1552 Words   |  7 PagesThe ideology that gender is socially constructed is a view that has been present in a number of philosophical, sociological and psychological theories. This view shares an understanding that gender is a product of enculturation through a prescribed ideal, as well as determines what is considered socially appropriate behaviour for a person of a specific gender. Society is shaped globally through social order. Each culture and society share a social order that is defined as a particular set of customsRead MoreGender Roles And Attitudes Of A Teacher s Practice1189 Words   |  5 PagesThe present essay attempts to demonstrate the stereot ypes around gender and and it’s relation to a teacher’s practice. In order for this objective to be met, the theory of gender will be introduced, followed by the stereotypes regarding the gender ‘’roles’’. Moreover the role of culture in the creation of gender roles and how popular culture-media carry stereotypes on children will be presented. This aims to show how a teacher can combat or prevent those stereotypes through her thoughtful, carefulRead MoreEssay about Socialization and the Learning of Gender Roles886 Words   |  4 Pages[Macionis et al. p 55] The concept of socialization is that our actions are driven/learned by culture. Socialization is also the foundation of personality, which we build by internalizing our surroundings. Through the lifelong process of socialization, society transmits culture from one generation to the next. A good example of socialization is the learning of gender roles. Anthropologist Margaret Mead reasoned that if gender reflects biological facts of sex, that people everywhere in the world would defineRead MoreFantomina: the Manipulator of Situations1503 Words   |  7 Pagesin France. Haywood’s Fantomina represents an important moment in the evolution of gender constructions in the eighteenth century.This research essay is from short story Fantomina.Eliza Haywood Fantomina perceives that gender categories can easily be changed by showing that nothing is ever fixed.You have the power to manipulate any situation you are faced with. There are many instances where the reversal of gender categories is highlited. On page 1458,Haywood says ‘She was young,a stranger to theRead MoreEntrepreneurial Education And Entrepreneurship Education1511 Words   |  7 PagesAlthough it is a given that many research findings demonstrate an overall agreement on entrepreneurial education and that entrepreneurship can be learned and taught to a certain extent, agreements around the entrepreneurship education curriculum such as teaching methods, appropriateness of concepts and educational course content, are not quite in unison amongst scholars (Robinson and Hayenes 1991; Kuratko 2005; Pittaway and Cope 2007; Lià ±Ãƒ ¡n et al 2011). Therefore it can be assumed that entrepreneurialRead MoreSexual Identity And Gender Expression1399 Words   |  6 PagesTo conceptualise sexual identity and gender expression, Judith Butler (1990) proposes a poststructuralist perspective; that gendered behaviour (masculinity and femininity) is le arned, a performative act, and that gender is constructed through a ‘heterosexual matrix’. She describes this as [A] hegemonic/epistemic model of gender intelligibility that assumes that for bodies to cohere and make sense there must be a stable sex expressed through a stable gender (masculine expresses discursive male, feminineRead MoreEssay about Sociological Analysis of Sexual Assault1554 Words   |  7 Pagesmay also bring a private action called a civil suit, suing the person who assaulted her or him for money damages.This cause of action is distinguishable from a criminal action, which is defined by a different body of law, has a different burden of proof, and has different results. The civil suit is generally defined by court cases, rather than by treatment of law, as is criminal justice. The macro-diachronic approach is a modern theoretical model of crime and deviance, which specifically attemptsRead MoreCulture, Culture And Culture Essay1321 Words   |  6 PagesCulture, in Sociology, is a concept developed during XVIII and XIX centuries that has had various definitions. One exhaustive definition is in Browne (2015, p. 31): â€Å"Culture refers to the language, beliefs, values and norms, customs, dress, diet, roles, knowledge and skills, and all the other things that people learn that make up the ‘way of life’ of any society† So when we use the expression ‘Italian culture’ we know that we are talking about the entire set of believes, knowledge and the whole wayRead MoreThe Evidence that Socialisation Plays a Major Part in Shaping Human Behaviour869 Words   |  4 PagesThe Evidence that Socialisation Plays a Major Part in Shaping Human Behaviour Socialisation is the lifelong process by which human behaviour is shaped through experience in social institutions (e.g. family, which is a crucial factor in primary socialisation). Through socialization, individuals learn the values, norms (formal and informal rules), and beliefs of a given society. In considering the nature of the self, it is necessary to include a still more fundamentalRead MoreSexual Identity And Gender Roles Essay1398 Words   |  6 Pagesand intensity of how the sexes, gender, gender roles and gender stereotypes are differentiated. Before we get to understand how they are differentiated, it s good to first understand the meaning of each term. Sex is the biological and physiological differences between men and women, sex roles are the behaviours and patterns of activities that the men and women may engage in which are directly related to their biological differences while gender are the behaviours or patterns of activities that the

Tuesday, May 5, 2020

Enzymes and the Way that They Work

Question: Describe Enzymes and the way that they work. Answer: Structure and function of the enzyme Enzymes are the protein macromolecules. The enzyme possesses three structures namely Primary, Secondary and Tertiary. The amino acids remain interlinked with each other with the help of peptide bonds (primary structure). The NH2 (amino group) and the Oxygen from the COOH (carboxyl group) of the amino acids interact with each other with the help of hydrogen bonding. This interaction leads to -helical and -sheet conformations, which is known as the secondary structure. Furthermore, this secondary structure folds up to form the 3-dimensional tertiary structure which results in the formation of active sites (which binds substrate), allosteric sites in the enzyme. Sometimes inorganic ions like Mg2+, Fe2+, Zn2+ (cofactors) and organic substances (coenzymes remain attached with the enzymes (or apoenzymes) via covalent bonds to form holoenzymes (Cox 2013). Figure 1: A simple structure of an enzyme Source: (Cox 2013) The primary and most important function of an enzyme is to accelerate the rate of a reaction by acting as a biocatalyst. Moreover, the tertiary structure had provided the enzyme with an active/catalytic site. This active site of the enzyme binds specifically with a substrate to produce a final product. For example, enzyme Lipase binds to its specific lipid substrate to form glycerol and fatty acids as products (Berg, Stryer and Tymoczko 2015). Figure 2: Image showing the function of the enzyme that includes the substrate binding and product formation Source: (Berg, Stryer and Tymoczko 2015) Concept of activation energy In a biochemical process, the amount of energy required to start a reaction is known as the activation energy, and it is symbolized as à Ã‚ ªG. Moreover, it is a scientifically proven fact that both reactants (substrate) and products possess a particular energy (Armstrong and Hirst 2015). The transformation of a substrate to product requires a transition phase that has a higher energy value (activation energy). In other words, the substrate requires a higher energy to activate its transformation process to produce its final products. On the other hand, the enzyme lowers this activation energy resulting in a faster reaction rate (Cox 2013). Figure 3: The figure shows the activation energy required to transform a substrate to a product with and without an enzyme Source: (Cox 2013) Lock and key and Induced fit models of enzyme action Lock and key model In 1894, Fischer compared the activity of enzyme and substrate with lock and key. One enzyme can act only on a particular type of substrate just as a key fits a particular lock. Each enzyme possesses a specific part (active site), to which the specific part of the substrate is joined. Biochemical reactions occur in the active site where the enzyme-substrate complex is formed by forming bonds within it (Berg, Stryer and Tymoczko 2015). The bond loosens when the chemical reaction is over, and the product is formed, and the enzyme gets free (Gspri, Vrna, Szappanos and Perczel 2010). Figure 4: The lock and key model of enzyme-substrate interaction Source: (Gspri, Vrna, Szappanos and Perczel 2010) Induced fit theory The induced fit theory is the modernized version of Lock and Key Model. According to this model, as the substrate gets closer, the active site of the enzyme tends to change its shape and conformation. Moreover, scientists have found that the change in the structure of the active site of the enzyme is induced' by the approaching substrate molecule. This change in shape of the active site of the enzyme helps the substrate to easily fit' into the active site of the enzyme. This model of enzyme-substrate interaction is known as the induced fit theory. Moreover, it should be noted that only a specific substrate for a specific enzyme can only bring this conformational change in the active site of the enzyme (Csermely, Palotai and Nussinov 2010). Figure 5: Schematic diagram showing the concept of Induced fit theory Source: (Csermely, Palotai and Nussinov 2010) Effects of three external factors on enzyme The effects of three external factors (Temperature, pH and Enzyme and Substrate concentration) influences the property and functioning of an Enzyme. A detailed discussion is as follows - Temperature: The increase in temperature increases the vibrational energy that significantly affects the bonds present inside enzyme making it weaker. Moreover, it also results in the breakdown of the weaker bonds like hydrogen and ionic bonds inside the enzyme resulting in denaturation of the enzyme (Cox 2013). pH: The H+ and OH- ions interact with the hydrogen and ionic bonds of the enzyme by repelling or attracting them towards itself. This interference results in the change of conformation of the active site of the enzyme that ultimately leads to the impairment of the enzymatic activity (Leu and Zhu 2013). Enzyme and Substrate Concentration: Increase in Enzyme will give rise to an increased rate of reactions. This is because the fact that more enzymes will collide with the substrate resulting in a faster reaction. On the other hand, an increase in the substrate concentration will lead to a similar result as well. As a consequence of an increase in the substrate concentration, more substrate will collide and interact with the enzyme molecule which will produce a higher number of products (Berg, Stryer and Tymoczko 2015). Reference Armstrong, F.A. and Hirst, J., 2011. Reversibility and efficiency in electrocatalytic energy conversion and lessons from enzymes.Proceedings of the National Academy of Sciences,108(34), pp.14049-14054. Berg, J.M., Stryer, L. and Tymoczko, J.L., 2015.Stryer Biochemie. Springer-Verlag. Cox, M.M., 2013.Lehninger principles of biochemistry. Freeman. Csermely, P., Palotai, R. and Nussinov, R., 2010. Induced fit, conformational selection and independent dynamic segments: an extended view of binding events.Trends in biochemical sciences,35(10), pp.539-546. Gspri, Z., Vrnai, P., Szappanos, B. and Perczel, A., 2010. Reconciling the lock-and-key and dynamic views of canonical serine protease inhibitor action.FEBS letters,584(1), pp.203-206. Leu, S.Y. and Zhu, J.Y., 2013. Substrate-related factors affecting enzymatic saccharification of lignocelluloses: our recent understanding.Bioenergy Research,6(2), pp.405-415.